Discover Peace of Mind in Your Pregnancy Journey
Every pregnancy is unique, and our non-invasive prenatal testing (NIPT) is designed to provide expectant parents and healthcare providers with valuable insights into fetal health. Trusted by health care professionals across Canada, our advanced screening technology analyses fetal DNA from a simple maternal blood sample, allowing early detection of potential genetic conditions.
EarlyReveal Non-Invasive Prenatal Screening Test
The EarlyReveal prenatal screening test* (NIPS), also referred to as non-invasive prenatal testing (NIPT), is performed using a small amount of blood. The test has no risk of miscarriage and can be performed as early as 10 weeks into pregnancy. In addition to testing for the fetal sex, the EarlyReveal Trisomy Test also screens your pregnancy for common genetic conditions caused by extra or missing chromosomes, such as:
- Trisomy 21 (Down syndrome)
- Trisomy 18 (Edwards syndrome)
- Trisomy 13 (Patau syndrome)
- Sex chromosome aneuploidies:
- Monosomy X (Turner syndrome)
- XXY syndrome (Klinefelter syndrome)
- Trisomy X (Triple X syndrome)
- XYY syndrome (Jacobs syndrome)
We’ll be here to support you from the moment we receive your order – before and after you receive results. So go ahead and enjoy all the exclusive benefits of choosing EarlyReveal, including:
- Flexible testing as early as 10 weeks
- Easy-to-understand information about EarlyReveal Trisomy Test, at your fingertips 24/7
- Informed consent for genetic screening – available anytime
- >99% sensitivity and specificity
- Fast results within 3-5 business days of the lab receiving your sample
*NIPS is a screening test; screen-positive (high-risk) results should be confirmed through diagnostic testing.
Covered by the majority of Collective Insurance
Screening Performance
EarlyReveal™ trisomy test is performed on the world most advanced and recognized sequencing platform and has been evaluated for clinical performance in multiple studies, inclusive of >60 000 total venous and capillary samples*. Based on this data, expected failure rate is extremely low and the performance is >99% sensitivity and >99.9% specificity for trisomy 21, 18, and 13.
Genetic Conditions Screened
EarlyReveal NIPT is available to Moms who are at least 10 weeks into their pregnancy, including those with high-risk pregnancies, members of the general obstetric population (low risk), and those carrying singletons, twins, or who have undergone IVF. In addition to screening for trisomies 21, 18, and 13, NIPT can also detect a variety of other genetic conditions, offering valuable insights for expectant parents. Here’s a list of the genetic conditions screened:
Trisomy 21 - Down syndrome
This is the most common chromosomal abnormality, caused by an extra chromosome 21. It results in intellectual disabilities and medical challenges. Early diagnosis through NIPT enables better planning for medical care and educational support. Approximately 1 in 700 pregnancies is affected by Down syndrome.
Trisomy 18 - Edwards syndrome
Characterized by severe developmental delays, Edwards syndrome results from an extra chromosome 18. Most pregnancies with Trisomy 18 end in miscarriage, and only about 10% of live-born infants survive their first year. NIPT allows early detection to help families prepare for the outcome.
Trisomy 13 - Patau syndrome
This condition, caused by an extra chromosome 13, leads to severe intellectual and physical disabilities. Most pregnancies with Patau syndrome miscarry, and live-born babies often face multiple life-threatening health issues. Detection via NIPT offers families valuable information early in the pregnancy.
Sex Chromomose Aneuploidy: Monosomy X - Turner syndrome
Occurring in females, Turner syndrome results from a missing X chromosome and can lead to short stature, heart defects, and infertility. Early detection enables better management of medical needs throughout life.
Sex Chromomose Aneuploidy: XXY syndrome - Klinefelter syndrome
Affecting males with an extra X chromosome, this condition can lead to learning difficulties, infertility, and specific physical traits like taller stature. NIPT helps in identifying this early, ensuring appropriate interventions and care.
Sex Chromomose Aneuploidy: Trisomy X - Triple X syndrome
Females with three X chromosomes may be taller than average and could face mild learning or behavioral challenges. Early detection through NIPT allows parents and doctors to monitor potential developmental needs.
Sex Chromomose Aneuploidy: XYY syndrome - Jacobs syndrome
Males with an extra Y chromosome often develop typically, but some may have an increased risk of learning or behavioral difficulties. NIPT provides early information, allowing parents and doctors to plan for any needed support.
Microdeletion 1p36
This deletion on chromosome 1 leads to intellectual disabilities, heart defects, and various other health issues. NIPT helps in identifying this condition early, enabling a proactive approach to healthcare.
Microdeletion 4p- (Wolf-Hirschhorn syndrome)
Wolf-Hirschhorn syndrome (WHS) is a rare genetic disorder caused by a deletion of a portion of the short arm (p) of chromosome 4. This condition is characterized by distinctive facial features, intellectual disabilities, growth delays, and seizures. Other common issues include heart defects, skeletal abnormalities, and feeding difficulties. Early diagnosis is important for managing symptoms and providing supportive therapies. WHS occurs in approximately 1 in 50,000 births.
Microdeletion 5p- (cri-du-chat syndrome)
Characterized by a distinctive cat-like cry in infancy, this syndrome involves a deletion on chromosome 5, leading to intellectual disabilities and developmental delays. Early diagnosis allows for timely interventions.
Microdeletion 15q11.2 (Prader-Willi syndrome/Angelman syndrome)
Caused by the loss of specific genes on chromosome 15, this condition leads to muscle weakness, feeding difficulties in infancy, and excessive hunger in childhood, resulting in obesity.
A rare genetic disorder that leads to severe intellectual disability, developmental delays, and a distinctive happy demeanor.
NIPT provides early detection, allowing families to address the condition from birth.
Microdeletion 22q11.2 (DiGeorge)
Also known as DiGeorge syndrome, this genetic condition affects 1 in 2,000 pregnancies. It leads to heart defects, immune deficiencies, and developmental delays. Early diagnosis through NIPT allows families to prepare for specialized medical care and developmental interventions.
Trisomy of ALL chromosomes
Trisomy analysis checks for the presence of an extra chromosome in any of the 23 pairs of chromosomes, which can result in various conditions. While trisomies 21 (Down syndrome), 18 (Edwards syndrome), and 13 (Patau syndrome) are more common, trisomies can occur on any chromosome, potentially leading to developmental issues or miscarriage. NIPT can screen for these anomalies early in pregnancy, offering insights into the baby’s chromosomal health.
How do I order the test?
Order Your Test Online
You can easily purchase EarlyReveal NIPT testing online, with a full refund available up until your sample is collected. In certain provinces and territories, funding for NIPT may be available for those who meet specific high-risk criteria—please consult your healthcare provider to determine if you qualify. Additionally, some private health insurance plans may cover NIPT testing; we recommend checking with your insurance provider before making a purchase.
Access your personalized requisition
After completing your online purchase, you'll receive a confirmation email containing a requisition form customized specifically for your order.
Get your requisition form signed by your healthcare provider
Print the form from your order confirmation email and bring it to your provider for their signature. Unsigned requisitions cannot be processed, and labs will be unable to collect the necessary sample(s).
Collect your sample
Compare to other tests, to complete your EarlyReveal NIPT, only one blood sample is needed. Be sure to bring the signed requisition from your order confirmation, as samples cannot be collected without it. For a smoother experience, we recommend scheduling an appointment. Please contact info@earlyreveal.com to arrange your sample collection.
Get your results
Your test results will be sent directly to your healthcare provider within only 3-5 days of the laboratory receiving your sample, allowing them to review and discuss the findings with you. We recommend scheduling an appointment with your provider two weeks after your blood sample is collected for a thorough review of the results.
Choose between our EarlyReveal NIPT Tests
It's Simple, Fast, and Comprehensive.
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Order Your EarlyReveal Trisomy Test through your physician
The EarlyReveal NIPS Trisomy test offers accurate results for over 99% of women, regardless of ancestry, BMI, or if you're expecting twins or undergoing IVF. It provides reliable insights as early as a few weeks into your pregnancy, giving you peace of mind as you prepare for your journey into motherhood.
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Collect Your Sample
The blood collection takes less than 5 minutes and can be done at one of our partnered clinic or in the comfort of your own home.
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Get The Results
Digital results will be shared to you and your physician.
EarlyReveal’s privacy practices
EarlyReveal's DNA tests focus specifically on revealing your baby's gender during your pregnancy. Rest assured, our tests solely provide information about your baby's sex, without delving into details about your or your baby's health. After completing the test, we ensure the proper disposal of your blood sample, following clinical standards.
We understand the importance of privacy during this special time, and that's why EarlyReveal shares your results exclusively through the email address you provide. This approach is in line with our commitment to maintaining quality and safety regulations for the benefit of you and your growing family.
Frequently Asked Questions
What is the EarlyReveal™ Non-Invasive Prenatal Screen?
EarlyReveal NIPT is a blood-based screening test for pregnant parents. It screens for three of the most common chromosomal conditions seen in pregnancy - Down syndrome (trisomy 21), Edwards syndrome (trisomy 18) and Patau syndrome (trisomy 13). EarlyReveal™ NIPT can be performed as early as ten-week gestation through a simple blood collection which can be completed at home or at a partnered clinic.
How early can I take the EarlyReveal™ NIPT?
The EarlyReveal Non-Invasive Prenatal Screen can be performed as early as 10 weeks into your pregnancy, counting from the first day of your last menstrual period.
What are sex chromosome aneuploidies?
Sex chromosome aneuploidy occurs when a person has extra or missing sex chromosomes. Typically, females have two X chromosomes (XX), and males have one X and one Y chromosome (XY). However, a female with sex chromosome aneuploidy may have one X or three Xs instead of the usual two. A male with this condition might have two Xs and one Y (XXY), or one X and two Ys (XYY), instead of the typical XY pattern.
At birth, babies with sex chromosome aneuploidy usually appear like other girls or boys, as their genitalia do not reveal the condition. As they grow, they may be taller or shorter than average, face puberty-related issues, or experience infertility. While intellectual disability is uncommon, learning challenges like dyslexia can occur. These traits may be subtle and go unnoticed for years. Although individuals with sex chromosome aneuploidies may share some characteristics, each condition comes with unique features.
Can I order the EarlyReveal™ Non-Invasive Prenatal Screen for myself, or does it need to be ordered by my doctor?
You can order the EarlyReveal™ NIPT directly through our website. Because the EarlyReveal NIPT is a medical screen, a prescription from your physician is required before collecting your blood. Alternatively, your prenatal care provider can order the EarlyReveal™ NIPT on your behalf directly from EarlyReveal. If they do not have an account, they can contact us directly at info@earlyreveal.com
When will I receive my results?
Once the lab receives your sample, results are typically available within 3-5 business days. At that time, you’ll get an email notification and the results will be sent to your physician and yourself.
How accurate are the results of Hazel™ NIPS tests?
The EarlyReveal NIPT Test screens for trisomies 21, 18, and 13 with >99% sensitivity and specificity.
Any other questions?
You can reach us by phone or email weekdays from 9:00 AM - 5:00 PM (EST).
E-mail: info@earlyreveal.com
Phone: 1-888-972-8763